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May 19, 2024 · Generic Phenergan Used for Skin Allergy, Allergic Rhinitis, Allergic Conjunctivitis, Anaphylaxis, Nausea, Sedation, Motion Sickness Promethazine is a prescription medication with many uses, such as treatment or prevention of nausea , motion sickness , and allergy symptoms People also askPromethazine HCl has significant anticholinergic activity and is used as an antinauseant and antihistamine as well as for pre- and postoperative sedation and adjunctive therapy in pain relief It is well absorbed when administered orally, rectally, or by intramuscular injection, reaching peak effect within 20 minutes Note: This document provides detailed information about Phenergan Side Effects associated with promethazine Some dosage forms listed on this page may not apply specifically to the brand name Phenergan Applies to promethazine: oral syrup, oral tablet Other dosage forms: rectal suppository; solutionHow do you take Phenergan if you have motion sickness? 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